Intern
    Prof. Dr. Reinhold Tacke

    Publications 2004 - 2006


    25.  

    R. Ilg, C. Burschka, D. Schepmann, B. Wünsch, R. Tacke, Synthesis and pharmacological characterization of sila-panamesine, a sila-analogue of the sigma receptor ligand panamesine (EMD 57445), Organometallics 25, 5396-5408 (2006). Read more ...

    24.J.O. Daiss, C. Burschka, J.S. Mills, J.G. Montana, G.A. Showell, J.B.H. Warneck, R. Tacke, Synthesis, crystal structure analysis, and pharmacological characterization of desmethoxy-sila-venlafaxine, derivate of the serotorin/noradrenaline reuptake inhibitor sila-venlafaxine, J. Organomet. Chem. 691, 3589-3595 (2006). Read more ...

    23.

    X. Kästele, P. Klüfers, R. Tacke, Not unhydrolyzed at pH 8, Angew. Chem. 118, 3286-3288 (2006); Read more...  Angew. Chem. Int. Ed. 45, 3212-3214 (2006). Read more ...

    22.G.A. Showell, M.J. Barnes, J.O. Daiss, J.S. Mills, J.G. Montana, R. Tacke, J.B.H. Warneck, (R)-Sila-venlafaxine: a selective nonadrenaline reuptake inhibitor for the treatment of emesis, Bioorg. Med. Chem. Lett. 16, 2555-2558 (2006). Read more ...

    21.J.O. Daiß, C. Burschka, J.S. Mills, J.G. Montana, G.A. Showell, J.B.H. Warneck, R. Tacke, Sila-venlafaxine, a sila-analogue of the serotonin/noradrenaline reuptake inhibitor venlafaxine: synthesis, crystal structure analysis, and pharmacological characterization, Organometallics 25, 1188-1198 (2006). Read more ...

    20.R. Ilg, D. Troegel, C. Burschka, R. Tacke, Tetrafunctional silanes of the formula type Si(CH2X)4 (X = SAc, SH, OAc, OH, Br, I),  Organometallics 25, 548–551 (2006). Read more ...

    19.O. Seiler, M. Büttner, M. Penka, R. Tacke, Zwitterionic lambda5Si-Silicates with an SiS4C or SiS2O2C skeleton, compounds containing a square-pyramidal or trigonal-bipyramidal Si-coordination polyhedron, Organometallics 24, 6059–6052 (2005). Read more ...

    18.S. Dragota, R. Bertermann, C. Burschka, M. Penka, R. Tacke, Diastereo- and enantiomerically pure zwitterionic spirocyclic lambda5Si-[(ammonio)methyl]silicates with an SiO2N2C skeleton containing two bidentate chelate ligands derived from alpha-amino acids, Organometallics 24, 5560-5568 (2005). Read more ...

    17. R. Tacke, R. Bertermann, C. Burschka, S. Dragota, A zwitterionic spirocyclic pentacoordinate silicon compound synthesized in water by Si-O and Si-C bond cleavage, Angew. Chem. 117, 5426-5429 (2005); Angew. Chem. Int. Ed. 44, 5292-5295 (2005). Read more ...

    16.O. Seiler, C. Burschka, S. Metz, M. Penka, R. Tacke, Synthesis and structural characterization of neutral higher-coordinate silicon(IV) complexes with tridendate dianionic chelate ligands, Chem. Eur. J. 11, 7379-7386 (2005). Read more ...

    15.J.O. Daiss, C. Burschka, J.S. Mills, J.G. Montana, G.A. Showell, I. Fleming, C. Gaudon, D. Ivanova, H. Gronemeyer, R. Tacke, Synthesis, crystal structure analysis and pharmacological characterization of disila-bexarotene, a disila-analogue of the RXR-selective retinoid agonist bexarotene, Organometallics 24, 3192-3199 (2005). Read more ...

    14.

    O. Seiler, C. Burschka, M. Fischer, M. Penka, R. Tacke, Synthesis and structural characterization of novel neutral hexacoordinate silicon(IV) complexes with SiO2N4 skeletons containing cyanato-N or thiocyanoto-N ligands, Inorg. Chem. 44, 2337-2346 (2005). Read more  ...

    13.R. Tacke, T. Schmid, M. Merget, The SiOH-containing alpha-amino acid HOMe2SiCH2CH(NH2)COOH and its immobilization on silica via an Si-O-Si linkage, Organometallics 24, 1780-1783 (2005). Read more ...

    12.O. Seiler, C. Burschka, D. Schwahn, R. Tacke, Behavior of tri(n-butyl)ammonium bis[citrato(3-)-O1,O3,O6]silicate in aqueous solution: analysis of a sol-gel process by small angle neutron scattering, Inorg. Chem. 44, 2318-2325 (2005). Read more ...

    11.J.O. Daiß, C. Burschka, R. Tacke, Beta-Carbonylsilanes with a silacyclohexane skeleton and additional C-functionalized organyl groups at the silicon atom: synthesis, reactivity, and NMR-spectroscopic characterization, J. Organomet. Chem. 690, 678-684 (2005). Read more ...

    10.T. Heinrich, C. Burschka, M. Penka, B. Wagner, R. Tacke, 4-silapiperidine and 4-silapiperidinium derivatives: syntheses and structural characterization, J. Organomet. Chem. 690, 33-47 (2005). Read more ...

    9.R. Tacke, R. Bertermann, C. Burschka, S. Dragota, Hexacoordinate silicon(IV) complexes with SiO6 skeletons and multidentate ligands derived from citric acid or malic acid, Z. Anorg. Allg. Chem. 630 (2006-2012) 2004. Read more ...

    8.R. Tacke, R. Bertermann, C. Burschka, S. Dragota, M. Penka, I. Richter, Spirocyclic zwitterionic lambda5-Si-silicates with two bidentate ligands derived from alpha-amino acids or alpha-hydroxycarboxylic acids: synthesis, structure, and stereodynamics, J. Am. Chem. Soc. 126, 14493-14505 (2004). Read more ...

    7.J.O. Daiss, M. Albrecht, K. Mohr, R. Tacke, A novel silicon-based uncharged allosteric modulator for ligand binding to muscarinic M2 receptors: synthesis and pharmacological characterization, Organometallics 23, 6052-6057 (2004). Read more ...

    6.J.O. Daiss, K.A. Barth, C. Burschka, P. Hey, R. Ilg, K. Klemm, I. Richter, S.A. Wagner, R. Tacke, Synthesis of the multifunctional (chloromethyl)silanes Cl2Si(CH2Cl)2, (MeO)2Si(CH2Cl)2, RSi(CH2Cl)3 (R = 2,4,6-trimethoxyphenyl), ClSi(CH2Cl)3, MeOSi(CH2Cl)3, Si(CH2Cl)4, and ClCH2CH2Si(CH2Cl)3, Organometallics 23, 5193-5197 (2004). Read more ...

    5.J.O. Daiss, M. Penka, C. Burschka, R. Tacke, the Si-2,4,6-trimethoxyphenyl moiety as a novel protecting group in organosilicon chemistry: alternative synthesis of rac-sila-venlafaxine, Organometallics 23, 4987-4994 (2004). Read more ...

    4.R. Tacke, T. Schmid, M. Penka, C. Burschka, W. Bains, J. Warneck, Syntheses and pharmacological properties of the histaminic H1 antagonists sila-terfenadine-A, sila-terfenadine-B, disila-terfenadine, and sila-fexofenadine: a study of C/Si bioisosterism, Organometallics 23, 4915-4923 (2004). Read more ...

    3.R. Tacke, T. Heinrich, R. Bertermann, C. Burschka, A. Hamacher, M.U. Kassack, Sila-haloperidol: a silicon analogue of the dopamine (D2) receptor antagonist haloperidol, Organometallics 23, 4468-4477 (2004). Read more ...

    2.T. Heinrich, C. Burschka, J. Warneck, R. Tacke, Synthesis and pharmacological properties of silicon-containing 1,4-hidyrodropyridine derivatives: calcium channel antagonists and alpha1 adrenoceptpr antagonists of the sila-niguldipine type, Organometallics 23, 361-366 (2004). Read more ...

    1.

    O. Seiler, M. Penka, R. Tacke, [Benzilato(2-)-O1,O2]bis[1,3-diphenylpropane-1,3-

    dionato(1-)-O,O]silicon(IV): a neutral heteroleptic hexacoordinate silicon(IV) complex with an SiO6 skeleton, Inorg. Chim. Acta 357, 1955-1958 (2004). Read more ...
    Kontakt

    Prof. Dr. Reinhold Tacke
    Institut für Anorganische Chemie
    Am Hubland
    97074 Würzburg

    Tel.: +49 931 31-85250
    Fax: +49 931 31-84609
    E-Mail

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    Hubland Süd, Geb. C4