piwik-script

Intern
    Prof. Dr. Reinhold Tacke

      

    Sila-haloperidol: A Silicon Analogue of the Dopamine Antagonist Haloperidol

     


    Synthesis of Sila-haloperidol


    Receptor Affinities of Haloperidol and Sila-haloperidol for the Dopamine hD1, hD2, hD3, hD4, and hD5 Receptor (Radioligand Binding Studies)

     


    Metabolism of Haloperidol and Sila-haloperidol


    Major in vitro Metabolites of Sila-haloperidol (Human Liver Microsomes, MS/MS Studies)

     


    R. Tacke, T. Heinrich, R. Bertermann, C. Burschka, A. Hamacher, M. U. Kassack, Organometallics2004, 23, 4468–4477. more ...

    R. Tacke, F. Popp, B. Müller, B. Theis, C. Burschka, A. Hamacher, M. U. Kassack, D. Schepmann, B. Wünsch, U. Jurva, E. Wellner, ChemMedChem2008, 3, 152–164. more...

    R. Tacke, T. Heinrich (Amedis Pharmaceuticals Ltd.), UK Pat. Appl. GB 2382575 A (04.06.2003). more...